Effect of Morinda Lucida Leaf Extract on Ibuprofen Induced Nephrotoxicity Albino Rats

Morinda lucida ethanol stem bark extract dilution of ((500, 1000, 1500) mg /kg) body weight were administered to B1, B2, B3 groups subjected to ibuprofen induced nephrotoxicity. Histomorphological studies on target organ; kidney were harvested, weighed and processed. Ibuprofen toxic activities of the extracts treated groups (serum biochemical markers) and the relative organ index (ρ<0.05) in treated groups respectively produce significant changes. Target organ extract examinations offered some protection on glomerular and tubular degenerative changes while there are deterioration changes in B groups.